Tramadol is a opioid analgesic (Ultram ®; Johnson& Johnson).
Tramadol's mechanism as a drug to prolong erection is poorly misunderstood. It is thought to act on the µ-opiod receptor which reduces sensitivity as as well as inhibiting serotonin uptake which delays the ejaculation.
In 2 studies it has increased IELT from 1.7 minutes to 7.37 minutes and 19 seconds to 4 minutes. Further studies of this pill is needed.
IELT stands for intra-vaginal ejaculatory latency time and is the measured time of maintaining and erection from entry into the vagina to ejaculation.
Clomipramine is a tri-psychic antidepressant pill (Anafranil ®; Mallinckrodt pharmaceuticals)
This medicine is usually used in the treatment of obsessive-compulsive disorders and inhibits the reuptake of noradrenaline and serotonin.
When used on in on-demand studies it has shown to increase IELT (i.e.) by four times however it does have a high incidence of side effects
Serotonergic antidepressants (often called SSRI’s) have been used as medication to prolong erections and can delay premature ejaculation for several minutes.
They are drugs used in the treatment of depression and a side-effect was delayed ejaculation. A lower dose of these pills are given to prolong erections.
The side-effects include dry mouth, drowsiness, nausea, reduced libido and erectile dysfunction.
Four types of these pills are commonly used in the treatment of premature ejaculation. Fluoxetine (Prozac®; Eli Lilly, IN, USA), paroxetine (Paxil®; GlaxoSmithKline PLC, PA, USA), sertraline (Zoloft®; Pfizer, NY, USA) and citalopram (Celexa®; Forest Laboratories, NY, USA)
Dapoxetine is a new SSRI medication that has shown to be a potent serotonin reuptake transporter inhibitor. ((Priligy™ Johnson & Johnson, NJ, USA).
It acts in a short so it is good for on-demand medication to prolong ejaculation.
In several studies it is shown to improve IELT by up to 3 times if taken 1 to 3 hours before intercourse and is well tolerated.
Despite side-effects, pills to prolong your erection may be the only alternative for some men, however if you would like control your erection naturally without side effects get advice from a professional sex therapist - more info at www.ejaculation-control.org
Regards,
Sean Anthony.
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